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“Karena memang Airlangga itu dinilai sebagai ketua umum yang sebenarnya sukses. Membuat Golkar naik, suaranya dipilih di 2024 dan juga dianggap sebagai menteri ekonomi yang juga sukses. Jadi itu yang sebenarnya membuat tanda tanya,” kata Adi.
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Tapi sehari dua hari ini Airlangga secara terbuka mundur dan tentu saja membuat tanda tanya publik,” kata Adi.
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Di hari yang sama, Airlangga juga melakukan pertemuan dengan Presiden Jokowi, namun menteri koordinator perekonomian ini mengatakan isi percakapannya sebagai “update ekonomi”.
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In this analyze, we identified Aph1 mutations which have been Lively within the absence of nicastrin (NCT) using a yeast γ-secretase assay. We analyzed these Aph1 mutations from the existence of NCT; we observed which the L30F/T164A mutation is activating. When launched in mouse embryonic fibroblasts, the mutation enhanced cleavage. The Aph1 mutants manufactured more small and lengthy Aβs than did the wild-form Aph1, devoid of an obvious modulatory functionality. The mutants didn't improve the level of γ-secretase complex, suggesting that L30F/T164A enhances catalytic action. Our benefits give insights in the regulatory purpose of Aph1 in γ-secretase activity.
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